ATRX L1612P
Gene Variant Detail

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Gene ATRX
Variant L1612P
Impact List missense
Protein Effect unknown
Gene Variant Descriptions ATRX L1612P lies within the helicase ATP-binding domain of the Atrx protein (UniProt.org). L1612P has not been characterized in the scientific literature and therefore, its effect on Atrx protein function is unknown (PubMed, Feb 2026).
Associated Drug Resistance
Category Variants Paths

ATRX mutant ATRX L1612P

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Transcript NM_000489.6
gDNA chrX:g.77633687A>G
cDNA c.4835T>C
Protein p.L1612P
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
XM_006724668.4 chrX:g.77633687A>G c.4835T>C p.L1612P RefSeq GRCh38/hg38
XM_005262155 chrX:g.77633570A>G c.4835T>C p.L1612P RefSeq GRCh38/hg38
NM_000489.6 chrX:g.77633687A>G c.4835T>C p.L1612P RefSeq GRCh38/hg38
XM_005262153.5 chrX:g.77633684_77633685delTTinsCC c.4834_4835delTTinsCC p.L1612P RefSeq GRCh38/hg38
XM_047442191.1 chrX:g.77633687A>G c.4835T>C p.L1612P RefSeq GRCh38/hg38
XM_005262153 chrX:g.77633684_77633685delAAinsGG c.4834_4835delTTinsCC p.L1612P RefSeq GRCh38/hg38
XM_017029606 chrX:g.77633275A>G c.4835T>C p.L1612P RefSeq GRCh38/hg38
XM_006724666.5 chrX:g.77633570A>G c.4835T>C p.L1612P RefSeq GRCh38/hg38
NM_000489 chrX:g.77633687A>G c.4835T>C p.L1612P RefSeq GRCh38/hg38
XM_006724666 chrX:g.77633570A>G c.4835T>C p.L1612P RefSeq GRCh38/hg38
NM_000489.4 chrX:g.77633687A>G c.4835T>C p.L1612P RefSeq GRCh38/hg38
XM_005262155.4 chrX:g.77633570A>G c.4835T>C p.L1612P RefSeq GRCh38/hg38
XM_006724668.3 chrX:g.77633687A>G c.4835T>C p.L1612P RefSeq GRCh38/hg38
XM_006724668 chrX:g.77633687A>G c.4835T>C p.L1612P RefSeq GRCh38/hg38
XM_017029606.2 chrX:g.77633275A>G c.4835T>C p.L1612P RefSeq GRCh38/hg38
XM_006724666.4 chrX:g.77633570A>G c.4835T>C p.L1612P RefSeq GRCh38/hg38
XM_005262153.6 chrX:g.77633684_77633685delTTinsCC c.4834_4835delTTinsCC p.L1612P RefSeq GRCh38/hg38

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References
ATRX mutant high grade glioma not applicable N/A Guideline Diagnostic ATRX mutations aid in the diagnosis of gliomas (NCCN.org). detail...