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Gene RET
Variant C609G
Impact List missense
Protein Effect unknown
Gene Variant Descriptions RET C609G lies within the extracellular domain of the Ret protein (UniProt.org). C609G has been identified in the scientific literature (PMID: 8626834, PMID: 30763276, PMID: 24699901), but has not been biochemically characterized and therefore, its effect on Ret protein function is unknown (PubMed, Feb 2024).
Associated Drug Resistance
Category Variants Paths

RET mutant RET C609X RET C609G

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Transcript NM_020975.6
gDNA chr10:g.43113621T>G
cDNA c.1825T>G
Protein p.C609G
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
NM_020975 chr10:g.43113621T>G c.1825T>G p.C609G RefSeq GRCh38/hg38
NM_020630 chr10:g.43113621T>G c.1825T>G p.C609G RefSeq GRCh38/hg38
NM_001406763.1 chr10:g.43113621T>G c.1825T>G p.C609G RefSeq GRCh38/hg38
NM_001406765.1 chr10:g.43113621T>G c.1825T>G p.C609G RefSeq GRCh38/hg38
NM_001406743.1 chr10:g.43113621T>G c.1825T>G p.C609G RefSeq GRCh38/hg38
NM_001406759.1 chr10:g.43113621T>G c.1825T>G p.C609G RefSeq GRCh38/hg38
NM_001406744.1 chr10:g.43113621T>G c.1825T>G p.C609G RefSeq GRCh38/hg38
NM_001406760.1 chr10:g.43113621T>G c.1825T>G p.C609G RefSeq GRCh38/hg38
NM_020630.7 chr10:g.43113621T>G c.1825T>G p.C609G RefSeq GRCh38/hg38
NM_020975.5 chr10:g.43113621T>G c.1825T>G p.C609G RefSeq GRCh38/hg38
NM_020630.5 chr10:g.43113621T>G c.1825T>G p.C609G RefSeq GRCh38/hg38
NM_020975.6 chr10:g.43113621T>G c.1825T>G p.C609G RefSeq GRCh38/hg38

Filtering

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  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
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Sorting

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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References