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Gene | RET |
Variant | C609F |
Impact List | missense |
Protein Effect | unknown |
Gene Variant Descriptions | RET C609F lies within the extracellular domain of the Ret protein (UniProt.org). C609F has been identified in the scientific literature (PMID: 9068588, PMID: 24699901, PMID: 38339246), but has not been biochemically characterized and therefore, its effect on Ret protein function is unknown (PubMed, Feb 2025). |
Associated Drug Resistance | |
Category Variants Paths |
RET mutant RET C609X RET C609F |
Transcript | NM_020975.6 |
gDNA | chr10:g.43113622G>T |
cDNA | c.1826G>T |
Protein | p.C609F |
Source Database | RefSeq |
Genome Build | GRCh38/hg38 |