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Gene RET
Variant C611S
Impact List missense
Protein Effect unknown
Gene Variant Descriptions RET C611S lies within the extracellular domain of the Ret protein (UniProt.org). C611S has been identified in the scientific literature (PMID: 12734540, PMID: 25242331), but has not been biochemically characterized and therefore, its effect on Ret protein function is unknown (PubMed, Feb 2024).
Associated Drug Resistance
Category Variants Paths

RET mutant RET C611X RET C611S

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Transcript NM_020975.6
gDNA chr10:g.43113627T>A
cDNA c.1831T>A
Protein p.C611S
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
NM_020975.5 chr10:g.43113627T>A c.1831T>A p.C611S RefSeq GRCh38/hg38
NM_020975 chr10:g.43113627T>A c.1831T>A p.C611S RefSeq GRCh38/hg38
NM_001406759.1 chr10:g.43113627T>A c.1831T>A p.C611S RefSeq GRCh38/hg38
NM_020630.7 chr10:g.43113627T>A c.1831T>A p.C611S RefSeq GRCh38/hg38
NM_020630 chr10:g.43113627T>A c.1831T>A p.C611S RefSeq GRCh38/hg38
NM_001406744.1 chr10:g.43113627T>A c.1831T>A p.C611S RefSeq GRCh38/hg38
NM_001406743.1 chr10:g.43113627T>A c.1831T>A p.C611S RefSeq GRCh38/hg38
NM_020975.6 chr10:g.43113627T>A c.1831T>A p.C611S RefSeq GRCh38/hg38
NM_001406765.1 chr10:g.43113627T>A c.1831T>A p.C611S RefSeq GRCh38/hg38
NM_020630.5 chr10:g.43113627T>A c.1831T>A p.C611S RefSeq GRCh38/hg38
NM_001406760.1 chr10:g.43113627T>A c.1831T>A p.C611S RefSeq GRCh38/hg38
NM_001406763.1 chr10:g.43113627T>A c.1831T>A p.C611S RefSeq GRCh38/hg38

Filtering

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  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
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  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References