NTRK1 act mut
Gene Variant Detail

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Gene NTRK1
Variant act mut
Impact List unknown
Protein Effect gain of function
Gene Variant Descriptions NTRK1 act mut indicates that this variant results in a gain of function in the Ntrk1 protein. However, the specific amino acid change has not been identified.
Associated Drug Resistance
Category Variants Paths

NTRK1 mutant NTRK1 act mut

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No Variant Reference Transcript is Available.
No transcript is Available.

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.

Clinical Trial Phase Therapies Title Recruitment Status Covered Countries Other Countries
NCT03953235 Phase Ib/II GRT-C903 + GRT-R904 + Ipilimumab + Nivolumab A Study of a Personalized Cancer Vaccine Targeting Shared Neoantigens Completed USA 0
NCT06120075 Phase I AB801 AB801 + Docetaxel AB801 + Docetaxel + Zimberelimab A Study of AB801 Monotherapy and Combination Therapy in Participants With Advanced Malignancies (ARC-27) Active, not recruiting USA 0
NCT03556228 Phase Ib/II Pembrolizumab + VMD-928 VMD-928 VMD-928 Monotherapy and in Combination With Pembrolizumab to Treat TrkA Overexpression Driven Solid Tumors or Lymphoma Recruiting USA 1
NCT05435846 Phase I Capmatinib + Trametinib Capmatinib Plus Trametinib for the Treatment of Metastatic Non-small Cell Lung Cancer With MET Exon 14 Skipping Mutation Terminated USA 0
NCT06307795 Phase I ANS014004 A Study to Investigate ANS014004 in Participants With Locally Advanced or Metastatic Solid Tumors Recruiting USA | CAN 1
NCT05083481 Phase Ib/II ASP1570 + Pembrolizumab ASP1570 ASP1570 + Trifluridine-tipiracil hydrochloride ASP1570 + Docetaxel ASP1570 + Fluorouracil + Leucovorin + Oxaliplatin ASP1570 + Carboplatin + Pembrolizumab + Pemetrexed Disodium ASP1570 + Fluorouracil + Irinotecan + Leucovorin A Study of ASP1570 Taken by Itself, or ASP1570 Taken Together With Either Pembrolizumab, Standard Therapies, or Both, in Adults With Solid Tumors Terminated USA | FRA | ESP 3
NCT03175224 Phase Ib/II Vebreltinib APL-101 Study of Subjects With NSCLC With c-Met EXON 14 Skip Mutations and c-Met Dysregulation Advanced Solid Tumors (SPARTA) Recruiting USA | ITA | HUN | GBR | FRA | ESP | CAN | AUS 3
NCT05176665 Phase Ib/II EMB-01 EMB-01 in Patients With Advanced/Metastatic Gastrointestinal Cancers Recruiting USA 1