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| Gene | FLT3 |
| Variant | positive |
| Impact List | unknown |
| Protein Effect | unknown |
| Gene Variant Descriptions | FLT3 positive indicates the presence of FLT3 mRNA and/or protein. |
| Associated Drug Resistance | |
| Category Variants Paths |
FLT3 positive |
| Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
|---|---|---|---|---|---|---|
| NCT06325748 | Phase I | SENTI-202 | SENTI-202: Off-the-shelf Logic Gated CAR NK Cell Therapy in Adults With CD33 and/or FLT3 Blood Cancers Including AML/MDS | Recruiting | USA | AUS | 0 |
| NCT06786533 | Phase I | Cyclophosphamide + Fludarabine Anti-FLT3 CAR-T cells | Clinical Study of Anti-FLT3 CAR-T Cells for the Treatment of Relapsed/refractory AML | Recruiting | USA | 0 |
| NCT03904069 | Phase I | Anti-FLT3 CAR-T cells | Study Evaluating the Safety, Tolerability, and Efficacy of FLT3 CAR-T AMG 553 in FLT3-positive Relapsed/Refractory AML | Withdrawn | USA | 0 |
| NCT02846376 | Phase I | Ipilimumab Ipilimumab + Nivolumab Nivolumab | Single Agent and Combined Inhibition After Allogeneic Stem Cell Transplant (CPIT-002) | Terminated | USA | 0 |