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Gene | FLT3 |
Variant | positive |
Impact List | unknown |
Protein Effect | unknown |
Gene Variant Descriptions | FLT3 positive indicates the presence of the FLT3 gene, mRNA, and/or protein. |
Associated Drug Resistance | |
Category Variants Paths |
FLT3 positive |
Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
---|---|---|---|---|---|---|
NCT06786533 | Phase I | Cyclophosphamide + Fludarabine Anti-FLT3 CAR-T cells | Clinical Study of Anti-FLT3 CAR-T Cells for the Treatment of Relapsed/refractory AML | Recruiting | USA | 0 |
NCT02846376 | Phase I | Ipilimumab Ipilimumab + Nivolumab Nivolumab | Single Agent and Combined Inhibition After Allogeneic Stem Cell Transplant (CPIT-002) | Terminated | USA | 0 |
NCT03904069 | Phase I | Anti-FLT3 CAR-T cells | Study Evaluating the Safety, Tolerability, and Efficacy of FLT3 CAR-T AMG 553 in FLT3-positive Relapsed/Refractory AML | Withdrawn | USA | 0 |
NCT06325748 | Phase I | SENTI-202 | SENTI-202: Off-the-shelf Logic Gated CAR NK Cell Therapy in Adults With CD33 and/or FLT3 Blood Cancers Including AML/MDS | Recruiting | USA | AUS | 0 |