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Gene RET
Variant E623_L633del
Impact List deletion
Protein Effect unknown
Gene Variant Descriptions RET E623_L633del results in the deletion of 11 amino acids in the extracellular domain of the Ret protein from amino acids 623 to 633 (UniProt.org). E623_L633del has not been characterized in the scientific literature and therefore, its effect on Ret protein function is unknown (PubMed, Apr 2024).
Associated Drug Resistance
Category Variants Paths

RET mutant RET E623_L633del

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Transcript NM_020975.6
gDNA chr10:g.43113663_43114499del837
cDNA c.1867_1899del837
Protein p.E623_L633del11
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
NM_001406759.1 chr10:g.43113663_43114499del837 c.1867_1899del837 p.E623_L633del11 RefSeq GRCh38/hg38
NM_001406772.1 chr10:g.43116710_43118383del1674 c.1867_1899del1674 p.V623_S633del11 RefSeq GRCh38/hg38
NM_001406779.1 chr10:g.43121979_43122011del33 c.1867_1899del33 p.S623_S633del11 RefSeq GRCh38/hg38
NM_001406769.1 chr10:g.43116710_43118383del1674 c.1867_1899del1674 p.V623_S633del11 RefSeq GRCh38/hg38
NM_001406771.1 chr10:g.43118393_43118425del33 c.1867_1899del33 p.L623_L633del11 RefSeq GRCh38/hg38
NM_001406764.1 chr10:g.43114596_43114628del33 c.1867_1899del33 p.K623_F633del11 RefSeq GRCh38/hg38
NM_001406780.1 chr10:g.43121979_43122011del33 c.1867_1899del33 p.S623_S633del11 RefSeq GRCh38/hg38
NM_001406783.1 chr10:g.43123762_43123794del33 c.1867_1899del33 p.K623_N633del11 RefSeq GRCh38/hg38
NM_001406786.1 chr10:g.43123762_43123794del33 c.1867_1899del33 p.K623_N633del11 RefSeq GRCh38/hg38
NM_001406765.1 chr10:g.43113663_43114634del972 c.1867_1899del972 p.E623_R633del11 RefSeq GRCh38/hg38
NM_020975.5 chr10:g.43113663_43114499del837 c.1867_1899del837 p.E623_L633del RefSeq GRCh38/hg38
NM_001406767.1 chr10:g.43116602_43116634del33 c.1867_1899del33 p.F623_T633del11 RefSeq GRCh38/hg38
NM_020630.5 chr10:g.43113663_43114499del837 c.1867_1899del837 p.E623_L633del11 RefSeq GRCh38/hg38
NM_020630 chr10:g.43113663_43114499del837 c.1867_1899del837 p.E623_L633del11 RefSeq GRCh38/hg38
NM_001406789.1 chr10:g.43126587_43126619del33 c.1867_1899del33 p.L623_I633del11 RefSeq GRCh38/hg38
NM_001406770.1 chr10:g.43116602_43116634del33 c.1867_1899del33 p.F623_T633del11 RefSeq GRCh38/hg38
NM_020975 chr10:g.43113663_43114499del837 c.1867_1899del837 p.E623_L633del11 RefSeq GRCh38/hg38
NM_001406787.1 chr10:g.43123769_43123801del33 c.1868_1900del33 p.G623_S633del11 RefSeq GRCh38/hg38
NM_001406790.1 chr10:g.43126587_43126619del33 c.1867_1899del33 p.L623_I633del11 RefSeq GRCh38/hg38
NM_001406766.1 chr10:g.43116602_43116634del33 c.1867_1899del33 p.F623_T633del11 RefSeq GRCh38/hg38
NM_001406768.1 chr10:g.43114732_43116611del1880 c.1868_1900del1880 p.I623_R633del11 RefSeq GRCh38/hg38
NM_020630.7 chr10:g.43113663_43114499del837 c.1867_1899del837 p.E623_L633del11 RefSeq GRCh38/hg38
NM_001406743.1 chr10:g.43113663_43114499del837 c.1867_1899del837 p.E623_L633del11 RefSeq GRCh38/hg38
NM_001406774.1 chr10:g.43118480_43119562del1083 c.1867_1899del1083 p.G623_K633del11 RefSeq GRCh38/hg38
NM_001406788.1 chr10:g.43126587_43126619del33 c.1867_1899del33 p.L623_I633del11 RefSeq GRCh38/hg38
NM_001406778.1 chr10:g.43119731_43120098del368 c.1867_1899del368 p.L623_L633del11 RefSeq GRCh38/hg38
NM_001406791.1 chr10:g.43126707_43126739del33 c.1867_1899del33 p.E623_A633del11 RefSeq GRCh38/hg38
NM_001406776.1 chr10:g.43119731_43120098del368 c.1867_1899del368 p.L623_L633del11 RefSeq GRCh38/hg38
NM_001406773.1 chr10:g.43118393_43118425del33 c.1867_1899del33 p.L623_L633del11 RefSeq GRCh38/hg38
NM_001406784.1 chr10:g.43123727_43123759del33 c.1868_1900del33 p.P623_L633del11 RefSeq GRCh38/hg38
NM_001406763.1 chr10:g.43113663_43114634del972 c.1867_1899del972 p.E623_R633del11 RefSeq GRCh38/hg38
NM_001406744.1 chr10:g.43113663_43114499del837 c.1867_1899del837 p.E623_L633del11 RefSeq GRCh38/hg38
NM_001355216.1 chr10:g.43120102_43120134del33 c.1867_1899del33 p.A623_K633del11 RefSeq GRCh38/hg38
NM_001406781.1 chr10:g.43121979_43122011del33 c.1867_1899del33 p.S623_S633del11 RefSeq GRCh38/hg38
NM_020975.6 chr10:g.43113663_43114499del837 c.1867_1899del837 p.E623_L633del11 RefSeq GRCh38/hg38
NM_001355216.2 chr10:g.43120102_43120134del33 c.1867_1899del33 p.A623_K633del11 RefSeq GRCh38/hg38
NM_001406762.1 chr10:g.43114596_43114628del33 c.1867_1899del33 p.K623_F633del11 RefSeq GRCh38/hg38
NM_001406777.1 chr10:g.43119731_43120098del368 c.1867_1899del368 p.L623_L633del11 RefSeq GRCh38/hg38
NM_001406761.1 chr10:g.43114596_43114628del33 c.1867_1899del33 p.K623_F633del11 RefSeq GRCh38/hg38
NM_001406785.1 chr10:g.43123753_43123785del33 c.1867_1899del33 p.N623_R633del11 RefSeq GRCh38/hg38
NM_001406775.1 chr10:g.43119731_43120098del368 c.1867_1899del368 p.L623_L633del11 RefSeq GRCh38/hg38
NM_001406760.1 chr10:g.43113663_43114499del837 c.1867_1899del837 p.E623_L633del11 RefSeq GRCh38/hg38
NM_001406782.1 chr10:g.43121979_43122011del33 c.1867_1899del33 p.S623_S633del11 RefSeq GRCh38/hg38

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

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  • Click on any column header arrows to sort by that column
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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References