ATRX E607K
Gene Variant Detail

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Gene ATRX
Variant E607K
Impact List missense
Protein Effect unknown
Gene Variant Descriptions ATRX E607K does not lie within any known functional domains of the Atrx protein (UniProt.org). E607K has not been characterized in the scientific literature and therefore, its effect on Atrx protein function is unknown (PubMed, Jan 2026).
Associated Drug Resistance
Category Variants Paths

ATRX mutant ATRX E607K

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Transcript NM_000489.6
gDNA chrX:g.77683437C>T
cDNA c.1819G>A
Protein p.E607K
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
XM_006724668 chrX:g.77683437C>T c.1819G>A p.E607K RefSeq GRCh38/hg38
XM_017029601.3 chrX:g.77683347C>T c.1819G>A p.E607K RefSeq GRCh38/hg38
NM_000489.4 chrX:g.77683437C>T c.1819G>A p.E607K RefSeq GRCh38/hg38
NM_000489.6 chrX:g.77683437C>T c.1819G>A p.E607K RefSeq GRCh38/hg38
XM_017029601 chrX:g.77683347C>T c.1819G>A p.E607K RefSeq GRCh38/hg38
XM_047442191.1 chrX:g.77683437C>T c.1819G>A p.E607K RefSeq GRCh38/hg38
NM_000489 chrX:g.77683437C>T c.1819G>A p.E607K RefSeq GRCh38/hg38
XM_006724668.3 chrX:g.77683437C>T c.1819G>A p.E607K RefSeq GRCh38/hg38
XM_017029601.2 chrX:g.77683347C>T c.1819G>A p.E607K RefSeq GRCh38/hg38
XM_006724668.4 chrX:g.77683437C>T c.1819G>A p.E607K RefSeq GRCh38/hg38

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References
ATRX mutant high grade glioma not applicable N/A Guideline Diagnostic ATRX mutations aid in the diagnosis of gliomas (NCCN.org). detail...