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| Profile Name | AXL A273V |
| Gene Variant Detail | |
| Relevant Treatment Approaches |
| Molecular Profile | Indication/Tumor Type | Response Type | Relevant Treatment Approaches | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
|---|---|---|---|---|---|---|---|---|
| AXL A273V | lung non-small cell carcinoma | predicted - resistant | Erlotinib | Preclinical - Cell culture | Actionable | In a preclinical study, expression of AXL A273V in non-small cell lung cancer cells conferred resistance to Tarceva (erlotinib) in culture (Cancer Res 2018;78(13 Suppl): nr 4903). | detail... |