Molecular Profile Detail

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Profile Name BTK C481X
Gene Variant Detail

BTK C481X (unknown)

Relevant Treatment Approaches

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Clinical Trial Phase Therapies Title Recruitment Status Covered Countries Other Countries
NCT04115059 Phase I Dasatinib Dasatinib In Waldenstrom Macroglobulinemia Terminated USA 0
NCT02427451 Phase Ib/II Ibrutinib + Obinutuzumab + Venetoclax Bcl-2 Inhibitor GDC-0199 in Combination With Obinutuzumab and Ibrutinib in Treating Patients With Relapsed, Refractory, or Previously Untreated Chronic Lymphocytic Leukemia Active, not recruiting USA 0
NCT01644253 Phase I Idelalisib + Otlertuzumab + Rituximab Otlertuzumab + Rituximab Obinutuzumab + Otlertuzumab Ibrutinib + Otlertuzumab Bendamustine + Otlertuzumab Phase 1b Safety and Efficacy Study of TRU-016 Terminated USA 0
NCT05168930 Phase II Venetoclax + Zanubrutinib Zanubrutinib and Venetoclax in CLL (ZANU-VEN) Recruiting USA 0
NCT04043845 Phase I Ibrutinib + LY3214996 ERK 1/2 Signaling in Ibrutinib Resistant B-cell Malignancies Withdrawn 0
NCT03740529 Phase Ib/II Cyclophosphamide + Doxorubicin + Pirtobrutinib + Prednisone + Rituximab + Vincristine Sulfate Pirtobrutinib + Rituximab + Venetoclax Pirtobrutinib + Venetoclax Pirtobrutinib A Study of Oral LOXO-305 in Patients With Previously Treated CLL/SLL or NHL Completed USA | SWE | POL | ITA | GBR | FRA | CHE | AUS 2
NCT04305444 Phase II DTRMWXHS-12 + Everolimus + Pomalidomide Study of a Triple Combination Therapy, DTRM-555, in Patients With R/R CLL or R/R Non-Hodgkin's Lymphomas Terminated USA 0