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Profile Name | ATR del |
Gene Variant Detail | |
Relevant Treatment Approaches |
Molecular Profile | Indication/Tumor Type | Response Type | Relevant Treatment Approaches | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
---|---|---|---|---|---|---|---|---|
ATR del | colorectal cancer | sensitive | Indisulam | Preclinical - Cell culture | Actionable | In a preclinical study, Indisulam (E7070) inhibited viability of a colorectal cancer cell line with knockout of ATR in culture (PMID: 38789724). | 38789724 | |
ATR del | colorectal cancer | sensitive | E7820 | Preclinical - Cell culture | Actionable | In a preclinical study, E7820 inhibited viability of a colorectal cancer cell line with knockout of ATR in culture (PMID: 38789724). | 38789724 |