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Therapy Name | Indisulam |
Synonyms | |
Therapy Description |
Indisulam (E7070) is a sulfonamide that inhibits cell cycle progression, potentially leads to inhibition of tumor cell growth (PMID: 11561678, PMID: 29660836). |
Drug Name | Trade Name | Synonyms | Drug Classes | Drug Description |
---|---|---|---|---|
Indisulam | E7070|E-7070 | Indisulam (E7070) is a sulfonamide that inhibits cell cycle progression, potentially leads to inhibition of tumor cell growth (PMID: 11561678, PMID: 29660836). |
Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
---|---|---|---|---|---|---|---|
ATR del | colorectal cancer | sensitive | Indisulam | Preclinical - Cell culture | Actionable | In a preclinical study, Indisulam (E7070) inhibited viability of a colorectal cancer cell line with knockout of ATR in culture (PMID: 38789724). | 38789724 |
ATM del | colorectal cancer | sensitive | Indisulam | Preclinical - Cell culture | Actionable | In a preclinical study, Indisulam (E7070) inhibited viability of a colorectal cancer cell line with knockout of ATM in culture (PMID: 38789724). | 38789724 |
Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
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