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Profile Name FBXW7 inact mut
Gene Variant Detail

FBXW7 inact mut (loss of function)

Relevant Treatment Approaches mTORC1 Inhibitor

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Clinical Trial Phase Therapies Title Recruitment Status Covered Countries Other Countries
NCT04851119 Phase Ib/II BC2059 Tegavivint for the Treatment of Recurrent or Refractory Solid Tumors, Including Lymphomas and Desmoid Tumors Recruiting USA 0
NCT03718091 Phase II Berzosertib M6620 (VX-970) in Selected Solid Tumors Completed USA 0
NCT05867251 Phase Ib/II ARTS-021 + Fulvestrant + Ribociclib ARTS-021 + Letrozole + Ribociclib ARTS-021 + Fulvestrant + Palbociclib ARTS-021 + Letrozole + Palbociclib ARTS-021 + Carboplatin Abemaciclib + ARTS-021 + Fulvestrant Abemaciclib + ARTS-021 + Letrozole ARTS-021 + Fulvestrant ARTS-021 Study of AVZO-021 in Patients With Advanced Solid Tumors Recruiting USA 0