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| Profile Name | NRAS R68T NRAS D92N |
| Gene Variant Detail | |
| Relevant Treatment Approaches |
| Molecular Profile | Indication/Tumor Type | Response Type | Relevant Treatment Approaches | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
|---|---|---|---|---|---|---|---|---|
| NRAS R68T NRAS D92N | head and neck cancer | sensitive | JAB-3312 | Preclinical - Cell culture | Actionable | In a preclinical study, JAB-3312 inhibited viability of a head and neck cancer cell line harboring NRAS D92N and R68T in culture (PMID: 40333694). | 40333694 |