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| Profile Name | CSF1R L301S |
| Gene Variant Detail | |
| Relevant Treatment Approaches | CSF1R Inhibitor |
| Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
|---|---|---|---|---|---|---|---|
| CSF1R mutant | Erdheim-Chester disease | sensitive | Pexidartinib | Guideline | Actionable | Turalio (pexidartinib) is included in guidelines as first-line or subsequent-line therapy for patients with Erdheim-Chester disease harboring CSF1R mutations (NCCN.org). | detail... |