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| Molecular Profile | BRAF V600E |
| Therapy | Dabrafenib |
| Indication/Tumor Type | glioblastoma |
| Response Type | predicted - sensitive |
| Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
|---|---|---|---|---|---|---|---|
| BRAF V600E | glioblastoma | predicted - sensitive | Dabrafenib | Case Reports/Case Series | Actionable | In a clinical case study, a previously treated pediatric patient with epithelioid glioblastoma harboring BRAF V600E demonstrated stable disease for 10 months when treated with Tafinlar (dabrafenib) (PMID: 29621181). | 29621181 |
| PubMed Id | Reference Title | Details |
|---|---|---|
| (29621181) | Dabrafenib Treatment in a Patient with an Epithelioid Glioblastoma and BRAF V600E Mutation. | Full reference... |