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| Molecular Profile | FGFR3 over exp |
| Therapy | U0126 |
| Indication/Tumor Type | glioblastoma |
| Response Type | sensitive |
| Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
|---|---|---|---|---|---|---|---|
| FGFR3 over exp | glioblastoma | sensitive | U0126 | Preclinical | Actionable | In a preclinical study, U0126 inhibited downstream signaling and growth of glioblastoma cells over-expressing Fgfr3 in culture (PMID: 23298836). | 23298836 |
| PubMed Id | Reference Title | Details |
|---|---|---|
| (23298836) | The tumorigenic FGFR3-TACC3 gene fusion escapes miR-99a regulation in glioblastoma. | Full reference... |