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Molecular Profile | FGFR2 C382R |
Therapy | Erdafitinib |
Indication/Tumor Type | triple-receptor negative breast cancer |
Response Type | predicted - sensitive |
Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
---|---|---|---|---|---|---|---|
FGFR2 C382R | triple-receptor negative breast cancer | predicted - sensitive | Erdafitinib | Case Reports/Case Series | Actionable | In a clinical case study, Balversa (erdafitinib) treatment resulted in a partial response with a progression-free survival of 24.3 months and best objective response of -59% in a patient with a triple-negative breast cancer harboring FGFR2 C382R (reported as C383R) (PMID: 39226398). | 39226398 |
PubMed Id | Reference Title | Details |
---|---|---|
(39226398) | Understanding and Overcoming Resistance to Selective FGFR inhibitors Across FGFR2-Driven Malignancies. | Full reference... |