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Molecular Profile RET fusion
Therapy Selpercatinib
Indication/Tumor Type biliary tract cancer
Response Type sensitive

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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References
RET fusion biliary tract cancer sensitive Selpercatinib Guideline Actionable Retevmo (selpercatinib) is included in guidelines as second or later-line therapy for patients with biliary tract cancer harboring RET fusions (PMID: 39864891; ESMO.org). detail... 39864891
RET fusion biliary tract cancer sensitive Selpercatinib Guideline Actionable Retevmo (selpercatinib) is included in the Pan-Asian Guidelines Adaptation (PAGA) for biliary tract cancer patients harboring RET fusions who have progressed on or are intolerant of prior therapies (PMID: 39232586; ESMO.org). detail... 39232586
PubMed Id Reference Title Details
ESMO Clinical Practice Guidelines Full reference...
ESMO Clinical Practice Guidelines Full reference...
(39232586) Pan-Asian adapted ESMO Clinical Practice Guidelines for the diagnosis, treatment and follow-up of patients with biliary tract cancer. Full reference...
(39864891) ESMO Clinical Practice Guideline interim update on the management of biliary tract cancer. Full reference...