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| Molecular Profile | KIT V560E |
| Therapy | Sunitinib |
| Indication/Tumor Type | gastrointestinal stromal tumor |
| Response Type | predicted - sensitive |
| Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
|---|---|---|---|---|---|---|---|
| KIT V560E | gastrointestinal stromal tumor | predicted - sensitive | Sunitinib | Case Reports/Case Series | Actionable | In a clinical case study, Sutent (sunitinib) treatment resulted in a partial response and symptom improvement in a patient with gastrointestinal stromal tumor harboring KIT V560E, and in a preclinical study, Sutent (sunitinib) treatment decreased viability of the patient-derived organoid in culture (PMID: 35982969). | 35982969 |
| PubMed Id | Reference Title | Details |
|---|---|---|
| (35982969) | Patient-Derived Organoid Facilitating Personalized Medicine in Gastrointestinal Stromal Tumor With Liver Metastasis: A Case Report. | Full reference... |