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| Molecular Profile | KIT K558_V560del |
| Therapy | Imatinib |
| Indication/Tumor Type | gastrointestinal stromal tumor |
| Response Type | predicted - sensitive |
| Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
|---|---|---|---|---|---|---|---|
| KIT K558_V560del | gastrointestinal stromal tumor | predicted - sensitive | Imatinib | Case Reports/Case Series | Actionable | In a clinical case study, neoadjuvant Gleevec (imatinib) treatment resulted in a partial response in a patient with gastrointestinal stromal tumor harboring KIT K558_V560del (PMID: 40900786). | 40900786 |
| PubMed Id | Reference Title | Details |
|---|---|---|
| (40900786) | Case Report: Dramatic response to entritinib in a patient with gastrointestinal stromal tumor positive for NTRK3 fusion. | Full reference... |