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| Molecular Profile | KIT G565R KIT K642E |
| Therapy | Imatinib |
| Indication/Tumor Type | gastrointestinal stromal tumor |
| Response Type | predicted - sensitive |
| Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
|---|---|---|---|---|---|---|---|
| KIT G565R KIT K642E | gastrointestinal stromal tumor | predicted - sensitive | Imatinib | Case Reports/Case Series | Actionable | In a clinical case study, Gleevec (imatinib) treatment resulted in a partial metabolic response in a patient with gastrointestinal stromal tumor in the prostate harboring KIT G565R and K642E (PMID: 39263341). | 39263341 |
| PubMed Id | Reference Title | Details |
|---|---|---|
| (39263341) | Successful Perioperative and Surgical Treatment of a Rare Case of Extra-Gastrointestinal Stromal Tumor Arising in the Prostate Gland. | Full reference... |