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| PMID | (37832649) | ||||||||||||
| Authors | Hoelzer D, Bassan R, Boissel N, Roddie C, Ribera JM, Jerkeman M, ESMO Guidelines Committee. Electronic address: clinicalguidelines@esmo.org | ||||||||||||
| Title | ESMO Clinical Practice Guideline interim update on the use of targeted therapy in acute lymphoblastic leukaemia. | ||||||||||||
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| Molecular Profile | Treatment Approach |
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| Gene Name | Source | Synonyms | Protein Domains | Gene Description | Gene Role |
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| Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
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| Drug Name | Trade Name | Synonyms | Drug Classes | Drug Description |
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| Gene | Variant | Impact | Protein Effect | Variant Description | Associated with drug Resistance |
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| Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
|---|---|---|---|---|---|---|---|
| ABL1 fusion | acute lymphoblastic leukemia | sensitive | Dasatinib | Guideline | Actionable | Sprycel (dasatinib) is included in guidelines for patients with newly diagnosed Ph-like acute lymphoblastic leukemia harboring ABL1 fusion (PMID: 37832649; ESMO.org). | detail... 37832649 |