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Therapy Name | CUE-101 |
Synonyms | |
Therapy Description |
CUE-101 is a fusion protein consisting of an HLA-A*0201 complex linked to an HPV16 E7 epitope (aa 11-20), a reduced affinity version of interleukin-2, and an effector attenuated IgG1 Fc domain, which binds to HPV16 E7-specific T-cells, potentially activating a T-cell response against HPV16 E7-positive tumor cells (PMID: 31964784). |