CUE-101
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| Drug Name | CUE-101 |
| Trade Name | |
| Synonyms | CUE101|CUE 101|anti-HPV16 E7 fusion protein CUE-101 |
| Drug Descriptions |
CUE-101 is a fusion protein consisting of an HLA-A*0201 complex linked to an HPV16 E7 epitope (aa 11-20), a reduced affinity version of interleukin-2, and an effector attenuated IgG1 Fc domain, which binds to HPV16 E7-specific T-cells, potentially activating a T-cell response against HPV16 E7-positive tumor cells (PMID: 31964784). |
| DrugClasses | |
| CAS Registry Number | NA |
| NCIT ID | C162459 |
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| Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
|---|---|---|---|
| CUE-101 | CUE-101 | 0 | 3 |
| CUE-101 + Pembrolizumab | CUE-101 Pembrolizumab | 0 | 2 |
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