Therapy Detail
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| Therapy Name | INCAGN01949 + Vidutolimod |
| Synonyms | |
| Therapy Description | |
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| Drug Name | Trade Name | Synonyms | Drug Classes | Drug Description |
|---|---|---|---|---|
| INCAGN01949 | INCAGN1949|INCAGN 1949|INCAGN-1949 | OX40 Antibody 15 | INCAGN01949 is an agonistic monoclonal antibody that targets TNFRSF4 (OX40, CD134), potentially resulting in increased T-lymphocyte proliferation and enhanced antitumor immune response (PMID: 36316061). | |
| Vidutolimod | CMP-001|CYT003|CYT 003|CYT-003|ARB-1598|QbG10 | TLR9 Agonist 9 | Vidutolimod (CMP-001) comprises a Toll-like receptor 9 (TLR-9) agonist encapsulated within a virus-like particle, which may lead to enhanced antitumor immune response and inhibition of tumor growth (PMID: 34326162). |
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| Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
|---|
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- Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
- Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
- Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")
Sorting
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- Click on any column header arrows to sort by that column
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| Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
|---|---|---|---|---|---|---|
| NCT04387071 | Phase Ib/II | INCAGN01949 + Vidutolimod | CMP-001 and INCAGN01949 for Patients With Stage IV Pancreatic Cancer and Other Cancers Except Melanoma | Terminated | USA | 0 |
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