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Therapy Name | INCAGN01949 + Vidutolimod |
Synonyms | |
Therapy Description | |
Drug Name | Trade Name | Synonyms | Drug Classes | Drug Description |
---|---|---|---|---|
INCAGN01949 | INCAGN1949|INCAGN 1949|INCAGN-1949 | OX40 Antibody 14 | INCAGN01949 is an agonistic monoclonal antibody that targets TNFRSF4 (OX40, CD134), potentially resulting in increased T-lymphocyte proliferation and enhanced antitumor immune response (PMID: 36316061). | |
Vidutolimod | CMP-001|CYT003|CYT 003|CYT-003|ARB-1598|QbG10 | TLR9 Agonist 9 | Vidutolimod (CMP-001) comprises a Toll-like receptor 9 (TLR-9) agonist encapsulated within a virus-like particle, which may lead to enhanced antitumor immune response and inhibition of tumor growth (PMID: 34326162). |
Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
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Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
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NCT04387071 | Phase Ib/II | INCAGN01949 + Vidutolimod | CMP-001 and INCAGN01949 for Patients With Stage IV Pancreatic Cancer and Other Cancers Except Melanoma | Terminated | USA | 0 |