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Drug Name | INCAGN01949 |
Trade Name | |
Synonyms | INCAGN1949|INCAGN 1949|INCAGN-1949 |
Drug Descriptions |
INCAGN01949 is an agonistic monoclonal antibody that targets TNFRSF4 (OX40, CD134), potentially resulting in increased T-lymphocyte proliferation and enhanced antitumor immune response (PMID: 36316061). |
DrugClasses | OX40 Antibody 14 |
CAS Registry Number | NA |
NCIT ID | C129967 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
DPV-001 + INCAGN01949 + Retifanlimab | DPV-001 INCAGN01949 Retifanlimab | 0 | 0 |
INCAGN01949 | INCAGN01949 | 0 | 1 |
INCAGN01949 + Ipilimumab | INCAGN01949 Ipilimumab | 0 | 1 |
INCAGN01949 + Ipilimumab + Nivolumab | INCAGN01949 Ipilimumab Nivolumab | 0 | 1 |
INCAGN01949 + Nivolumab | INCAGN01949 Nivolumab | 0 | 1 |
INCAGN01949 + Vidutolimod | INCAGN01949 Vidutolimod | 0 | 1 |