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Therapy Name SRF388
Synonyms
Therapy Description

SRF388 is a monoclonal antibody that binds to interleukin 27 (IL27) and inhibits downstream signaling, which potentially modulates immune response and inhibits tumor growth (Journal for ImmunoTherapy of Cancer Nov 2019, 7 (Suppl 1) 283, Abs nr: P805).

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Drug Name Trade Name Synonyms Drug Classes Drug Description
SRF388 SRF-388|SRF 388 SRF388 is a monoclonal antibody that binds to interleukin 27 (IL27) and inhibits downstream signaling, which potentially modulates immune response and inhibits tumor growth (Journal for ImmunoTherapy of Cancer Nov 2019, 7 (Suppl 1) 283, Abs nr: P805).

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  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References

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  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

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  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.

Clinical Trial Phase Therapies Title Recruitment Status Covered Countries Other Countries
NCT04374877 Phase I SRF388 Study of SRF388 in Patients With Advanced Solid Tumors Recruiting USA 2


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