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Drug Name | Casdozokitug |
Trade Name | |
Synonyms | SRF-388|SRF 388|SRF388|CHS-388|CHS388|CHS 388|Casdozo |
Drug Descriptions |
Casdozokitug (CHS-388) is a monoclonal antibody that binds to interleukin 27 (IL27) and inhibits downstream signaling, which potentially modulates immune response and inhibits tumor growth (Journal for ImmunoTherapy of Cancer Nov 2019, 7 (Suppl 1) 283, Abs nr: P805; Immuno-Oncology and Technology 24 (2024):100783). |
DrugClasses | |
CAS Registry Number | 2643331-37-5 |
NCIT ID | C174410 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
Atezolizumab + Bevacizumab + Casdozokitug | Atezolizumab Bevacizumab Casdozokitug | 0 | 1 |
Bevacizumab + Casdozokitug + Toripalimab-tpzi | Bevacizumab Casdozokitug Toripalimab-tpzi | 0 | 1 |
Casdozokitug | Casdozokitug | 0 | 1 |
Casdozokitug + Pembrolizumab | Casdozokitug Pembrolizumab | 0 | 0 |