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Drug Name Casdozokitug
Trade Name
Synonyms SRF-388|SRF 388|SRF388|CHS-388|CHS388|CHS 388|Casdozo
Drug Descriptions

Casdozokitug (CHS-388) is a monoclonal antibody that binds to interleukin 27 (IL27) and inhibits downstream signaling, which potentially modulates immune response and inhibits tumor growth (Journal for ImmunoTherapy of Cancer Nov 2019, 7 (Suppl 1) 283, Abs nr: P805; Immuno-Oncology and Technology 24 (2024):100783).

DrugClasses
CAS Registry Number 2643331-37-5
NCIT ID C174410

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Therapy Name Drugs Efficacy Evidence Clinical Trials
Atezolizumab + Bevacizumab + Casdozokitug Atezolizumab Bevacizumab Casdozokitug 0 1
Bevacizumab + Casdozokitug + Toripalimab-tpzi Bevacizumab Casdozokitug Toripalimab-tpzi 0 1
Casdozokitug Casdozokitug 0 1
Casdozokitug + Pembrolizumab Casdozokitug Pembrolizumab 0 0


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