Therapy Detail
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| Therapy Name | MRG002 |
| Synonyms | |
| Therapy Description |
MRG002 is an antibody-drug conjugate (ADC) that consists of a humanized anti-ERBB2 (HER2) IgG1 antibody linked to the cytotoxic agent monomethyl auristatin E (MMAE), which may have antitumor activity against ERBB2 (HER2)-positive tumors (PMID: 38772302) |
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| Drug Name | Trade Name | Synonyms | Drug Classes | Drug Description |
|---|---|---|---|---|
| MRG002 | MRG 002|MRG-002|Trastuzumab vedotin | HER2 (ERBB2) Antibody-Drug Conjugate 36 | MRG002 is an antibody-drug conjugate (ADC) that consists of a humanized anti-ERBB2 (HER2) IgG1 antibody linked to the cytotoxic agent monomethyl auristatin E (MMAE), which may have antitumor activity against ERBB2 (HER2)-positive tumors (PMID: 38772302) |
Filtering
- Case insensitive filtering will display rows if any text in any cell matches the filter term
- Use simple literal full or partial string matches
- Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
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- Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")
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| Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
|---|
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- Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
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- Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")
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- Click on any column header arrows to sort by that column
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| Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
|---|---|---|---|---|---|---|
| NCT04492488 | Phase Ib/II | MRG002 | A Study of MRG002 in Patients With HER2-Positive Advanced Solid Tumors and Locally Advanced or Metastatic Gastric/Gastroesophageal Junction (GEJ) Cancer | Active, not recruiting | USA | 0 |
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