Therapy Detail
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| Therapy Name | GEN1044 |
| Synonyms | |
| Therapy Description |
GEN1044 is a recombinant bispecific antibody that targets the human T-cell co-receptor CD3 and the oncofetal antigen 5T4, potentially leading to a cytotoxic T-cell response and inhibition of tumor cell cell proliferation (NCI Drug Dictionary). |
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| Drug Name | Trade Name | Synonyms | Drug Classes | Drug Description |
|---|---|---|---|---|
| GEN1044 | GEN 1044|GEN-1044|DuoBody-CD3x5T4|Anti-CD3/Anti-5T4 Bispecific Antibody GEN1044 | CD3 Antibody 119 | GEN1044 is a recombinant bispecific antibody that targets the human T-cell co-receptor CD3 and the oncofetal antigen 5T4, potentially leading to a cytotoxic T-cell response and inhibition of tumor cell cell proliferation (NCI Drug Dictionary). |
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- Use simple literal full or partial string matches
- Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
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- Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")
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| Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
|---|
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- Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
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- Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")
Sorting
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- Click on any column header arrows to sort by that column
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| Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
|---|---|---|---|---|---|---|
| NCT04424641 | Phase Ib/II | GEN1044 | A Study on the Safety of GEN1044 (DuoBody-CD3x5T4) in Subjects With Malignant Solid Tumors | Terminated | USA | ISR | ESP | DNK | 0 |
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