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Therapy Name GEN1044
Synonyms
Therapy Description

GEN1044 is a recombinant bispecific antibody that targets the human T-cell co-receptor CD3 and the oncofetal antigen 5T4, potentially leading to a cytotoxic T-cell response and inhibition of tumor cell cell proliferation (NCI Drug Dictionary).

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Drug Name Trade Name Synonyms Drug Classes Drug Description
GEN1044 GEN 1044|GEN-1044|DuoBody-CD3x5T4|Anti-CD3/Anti-5T4 Bispecific Antibody GEN1044 CD3 Antibody 99 GEN1044 is a recombinant bispecific antibody that targets the human T-cell co-receptor CD3 and the oncofetal antigen 5T4, potentially leading to a cytotoxic T-cell response and inhibition of tumor cell cell proliferation (NCI Drug Dictionary).

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

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  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.

Clinical Trial Phase Therapies Title Recruitment Status Covered Countries Other Countries
NCT04424641 Phase Ib/II GEN1044 A Study on the Safety of GEN1044 (DuoBody-CD3x5T4) in Subjects With Malignant Solid Tumors Terminated USA | ISR | ESP | DNK 0


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