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Therapy Name ISB 1342
Synonyms
Therapy Description

ISB 1342 (GBR 1342) is a bispecific antibody that binds CD3 and CD38, potentially resulting in cytotoxic activity against CD38-positive cells (Journal of Clinical Oncology 2018 36:15_suppl, TPS3132).

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Drug Name Trade Name Synonyms Drug Classes Drug Description
ISB 1342 ISB-1342|ISB1342|GBR 1342|GBR1342|GBR-1342 CD3 Antibody 99 CD38 Antibody 20 ISB 1342 (GBR 1342) is a bispecific antibody that binds CD3 and CD38, potentially resulting in cytotoxic activity against CD38-positive cells (Journal of Clinical Oncology 2018 36:15_suppl, TPS3132).

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  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.

Clinical Trial Phase Therapies Title Recruitment Status Covered Countries Other Countries
NCT03309111 Phase I ISB 1342 Study of GBR 1342, a CD38/CD3 Bispecific Antibody, in Subjects With Previously Treated Multiple Myeloma Completed USA | FRA 0


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