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Therapy Name | CG0070 + Dodecyl Maltoside |
Synonyms | |
Therapy Description | |
Drug Name | Trade Name | Synonyms | Drug Classes | Drug Description |
---|---|---|---|---|
CG0070 | Oncolytic adenovirus encoding GM-CSF|Cretostimogene Grenadenorepvec|CG-0070 | CG0070 is a recombinant adenovirus that selectively infects, replicates and produces GM-CSF in tumor cells, which leads to tumor lysis and cytotoxic T cell-mediated tumor cell death (PMID: 16397056, PMID: 28755959). | ||
Dodecyl Maltoside | DDM|Dodecyl-beta-D-maltoside|n-Dodecyl-B-D-maltoside |
Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
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Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
---|---|---|---|---|---|---|
NCT06567743 | Phase II | CG0070 + Dodecyl Maltoside | Brief Title: Phase 2 Study to Evaluate Safety and Efficacy of Cretostimogene Grenadenorepvec in High-Risk NMIBC | Recruiting | USA | 0 |
NCT04452591 | Phase III | CG0070 + Dodecyl Maltoside | Study of CG0070 Given in Patients With Non-Muscular Invasive Bladder Cancer ,Unresponsive to Bacillus-Calmette-Guerin (BOND-003) | Recruiting | USA | AUS | 3 |