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Drug Name CG0070
Trade Name
Synonyms Oncolytic adenovirus encoding GM-CSF|Cretostimogene Grenadenorepvec|CG-0070
Drug Descriptions

CG0070 is a recombinant adenovirus that selectively infects, replicates and produces GM-CSF in tumor cells, which leads to tumor lysis and cytotoxic T cell-mediated tumor cell death (PMID: 16397056, PMID: 28755959).

DrugClasses
CAS Registry Number 2414312-87-9
NCIT ID C48412

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Therapy Name Drugs Efficacy Evidence Clinical Trials
CG0070 CG0070 0 3
CG0070 + Dodecyl Maltoside CG0070 Dodecyl Maltoside 0 2
CG0070 + Dodecyl Maltoside + Pembrolizumab CG0070 Dodecyl Maltoside Pembrolizumab 0 1
CG0070 + Nivolumab CG0070 Nivolumab 0 1


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