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Drug Name | CG0070 |
Trade Name | |
Synonyms | Oncolytic adenovirus encoding GM-CSF|Cretostimogene Grenadenorepvec|CG-0070 |
Drug Descriptions |
CG0070 is a recombinant adenovirus that selectively infects, replicates and produces GM-CSF in tumor cells, which leads to tumor lysis and cytotoxic T cell-mediated tumor cell death (PMID: 16397056, PMID: 28755959). |
DrugClasses | |
CAS Registry Number | 2414312-87-9 |
NCIT ID | C48412 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
CG0070 | CG0070 | 0 | 3 |
CG0070 + Dodecyl Maltoside | CG0070 Dodecyl Maltoside | 0 | 2 |
CG0070 + Dodecyl Maltoside + Pembrolizumab | CG0070 Dodecyl Maltoside Pembrolizumab | 0 | 1 |
CG0070 + Nivolumab | CG0070 Nivolumab | 0 | 1 |