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Therapy Name | VT3989 |
Synonyms | |
Therapy Description |
VT3989 inhibits the auto-palymitoylation of TEAD, which leads to impaired YAP function, potentially leading to inhibition of tumor growth (Cancer Res (2023) 83 (8_Supplement): CT006). |
Drug Name | Trade Name | Synonyms | Drug Classes | Drug Description |
---|---|---|---|---|
VT3989 | VT-3989|VT 3989 | VT3989 inhibits the auto-palymitoylation of TEAD, which leads to impaired YAP function, potentially leading to inhibition of tumor growth (Cancer Res (2023) 83 (8_Supplement): CT006). |
Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
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Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
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NCT04665206 | Phase I | VT3989 | Study to Evaluate VT3989 in Patients With Metastatic Solid Tumors Enriched for Tumors With NF2 or mNF2 Gene Mutations | Recruiting | USA | AUS | 0 |