Therapy Detail
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| Therapy Name | Pocenbrodib |
| Synonyms | |
| Therapy Description |
FT-7051 inhibits CREB binding protein (CBP) and p300, which may lead to anti-tumor activities (PMID: 33785255). |
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| Drug Name | Trade Name | Synonyms | Drug Classes | Drug Description |
|---|---|---|---|---|
| Pocenbrodib | FT7051|FT 7051|FT7-051 | CBP/p300 inhibitor 13 | Pocenbrodib inhibits CREB binding protein (CBP) and p300, which potentially decreases proliferation of tumor cells expressing AR (Blood Cancer Discov (2024) 5 (2_Supplement): P33, NCI Drug Dictionary). |
Filtering
- Case insensitive filtering will display rows if any text in any cell matches the filter term
- Use simple literal full or partial string matches
- Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
- Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
- Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")
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| Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
|---|
Filtering
- Case insensitive filtering will display rows if any text in any cell matches the filter term
- Use simple literal full or partial string matches
- Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
- Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
- Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")
Sorting
- Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
- Click on any column header arrows to sort by that column
- Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.
| Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
|---|---|---|---|---|---|---|
| NCT04575766 | Phase I | Pocenbrodib | A Study of FT-7051 in Men With MCRPC | Terminated | USA | 0 |
| NCT06785636 | Phase Ib/II | Pocenbrodib Abiraterone + Pocenbrodib Olaparib + Pocenbrodib lutetium Lu 177 vipivotide tetraxetan + Pocenbrodib | Open-Label Study of Pocenbrodib and in Combination With Abiraterone Acetate, Olaparib, or 177Lu-PSMA-617 (P300) | Recruiting | USA | 0 |
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