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Therapy Name AZD7789
Synonyms
Therapy Description

AZD7789 is a bispecific antibody that targets both programmed cell death protein 1 (PDCD1) and TIM3, potentially leading to altered antitumor response including enhanced T-cell mediated cell lysis, and inhibition of tumor growth (NCI Drug Dictionary).

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Drug Name Trade Name Synonyms Drug Classes Drug Description
AZD7789 AZD 7789|AZD-7789 PD-L1/PD-1 antibody 128 TIM-3 Antibody 9 AZD7789 is a bispecific antibody that targets both programmed cell death protein 1 (PDCD1) and TIM3, potentially leading to altered antitumor response including enhanced T-cell mediated cell lysis, and inhibition of tumor growth (NCI Drug Dictionary).

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

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  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.

Clinical Trial Phase Therapies Title Recruitment Status Covered Countries Other Countries
NCT06366451 Phase I AZD2936 Pembrolizumab AZD7789 MEDI5752 PBI-MST-01 (NCT04541108) Substudy AZN-05: Intratumoral Microdosing of Rilvegostomig, Volrustomig, and Sabestomig in HNSCC Recruiting USA 0
NCT04931654 Phase Ib/II AZD7789 A Study to Assess the Safety and Efficacy of AZD7789 in Participants With Advanced or Metastatic Solid Cancer Active, not recruiting USA | TUR | NLD | FRA | ESP | CAN 4
NCT05216835 Phase Ib/II AZD7789 Safety and Preliminary Efficacy Assessment of AZD7789 in Patients With Relapsed or Refractory Classical Hodgkin Lymphoma Active, not recruiting USA | ITA | GBR | FRA | ESP | DNK | CAN 0


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