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Therapy Name GS-1811
Synonyms
Therapy Description

GS-1811 is a monoclonal antibody targeted against CCR8, which potentially induces antibody-dependent cell mediated cytotoxicity (ADCC) and depletion of tumor-infiltrating regulatory T cells (Tregs) (Cancer Res 2020;80(16 Suppl):Abstract nr 4532).

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Drug Name Trade Name Synonyms Drug Classes Drug Description
GS-1811 GS1811|GS 1811|JTX 1811|JTX1811|JTX-1811 CCR8 Antibody 9 GS-1811 is a monoclonal antibody targeted against CCR8, which potentially induces antibody-dependent cell mediated cytotoxicity (ADCC) and depletion of tumor-infiltrating regulatory T cells (Tregs) (Cancer Res 2020;80(16 Suppl):Abstract nr 4532).

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  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
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  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References

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  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

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  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.

Clinical Trial Phase Therapies Title Recruitment Status Covered Countries Other Countries
NCT05007782 Phase I GS-1811 GS-1811 + Pembrolizumab Study to Evaluate the Safety and Tolerability of GS-1811 as Monotherapy and in Combination With Pembrolizumab in Adults With Advanced Solid Tumors Recruiting USA | ESP | CAN | AUS 1


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