GS-1811
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| Drug Name | GS-1811 |
| Trade Name | |
| Synonyms | GS1811|GS 1811|JTX 1811|JTX1811|JTX-1811|Denikitug |
| Drug Descriptions |
GS-1811 is a monoclonal antibody targeted against CCR8, which potentially induces antibody-dependent cell mediated cytotoxicity (ADCC) and depletion of tumor-infiltrating regulatory T cells (Tregs) (Cancer Res 2020;80(16 Suppl):Abstract nr 4532). |
| DrugClasses | CCR8 Antibody 13 |
| CAS Registry Number | 2865822-82-6 |
| NCIT ID | C206899 |
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| Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
|---|---|---|---|
| Bevacizumab + GS-1811 + Trifluridine-tipiracil hydrochloride | Bevacizumab GS-1811 Trifluridine-tipiracil hydrochloride | 0 | 1 |
| GS-1811 | GS-1811 | 0 | 2 |
| GS-1811 + Nivolumab | GS-1811 Nivolumab | 0 | 1 |
| GS-1811 + Pembrolizumab | GS-1811 Pembrolizumab | 0 | 1 |
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