Therapy Detail
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| Therapy Name | LOXO-338 |
| Synonyms | |
| Therapy Description |
LOXO-338 inhibits BCL2, potentially leading to inhibition of tumor cell proliferation and tumor growth (Cancer Res 2021;81(13_Suppl):Abstract nr 1258). |
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| Drug Name | Trade Name | Synonyms | Drug Classes | Drug Description |
|---|---|---|---|---|
| LOXO-338 | LOXO338|LOXO 338|LY3847429|FCN338|FCN-338 | BCL2 inhibitor 29 | LOXO-338 inhibits BCL2, potentially leading to inhibition of tumor cell proliferation and tumor growth (Cancer Res 2021;81(13_Suppl):Abstract nr 1258). |
Filtering
- Case insensitive filtering will display rows if any text in any cell matches the filter term
- Use simple literal full or partial string matches
- Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
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- Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")
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| Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
|---|
Filtering
- Case insensitive filtering will display rows if any text in any cell matches the filter term
- Use simple literal full or partial string matches
- Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
- Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
- Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")
Sorting
- Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
- Click on any column header arrows to sort by that column
- Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.
| Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
|---|---|---|---|---|---|---|
| NCT05024045 | Phase I | LOXO-338 + Pirtobrutinib LOXO-338 | Study of Oral LOXO-338 in Patients With Advanced Blood Cancers | Active, not recruiting | USA | POL | ITA | FRA | 0 |
| NCT02632994 | Expanded access | LY3023414 LOXO-338 LY2503029 LOXO-260 | Master Rollover Protocol for Continued Safety Assessment of Study Drug | Available | USA | 0 |
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