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Therapy Name LOXO-260
Synonyms
Therapy Description

LOXO-260 is a selective RET inhibitor with activity against RET solvent front and gatekeeper mutations and fusions, with potential anti-tumor activity (J of Clin Oncol 40, no. 16_suppl (June 01, 2022) TPS8595).

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Drug Name Trade Name Synonyms Drug Classes Drug Description
LOXO-260 LOXO260|LOXO 260|LOX-19260|LY3838915 RET Inhibitor 53 LOXO-260 is a selective RET inhibitor with activity against RET solvent front and gatekeeper mutations and fusions, with potential anti-tumor activity (J of Clin Oncol 40, no. 16_suppl (June 01, 2022) TPS8595).

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  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
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  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References

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  • Case insensitive filtering will display rows if any text in any cell matches the filter term
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  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

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  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
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Clinical Trial Phase Therapies Title Recruitment Status Covered Countries Other Countries
NCT05241834 Phase I LOXO-260 A Study of LOXO-260 in Cancer Patients With a Change in a Particular Gene (RET) That Has Not Responded to Treatment Active, not recruiting USA 0


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