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Therapy Name P-BCMA-ALLO1 + Rimiducid
Synonyms
Therapy Description

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Drug Name Trade Name Synonyms Drug Classes Drug Description
P-BCMA-ALLO1 P-BCMA-ALLO 1|P-BCMA-ALLO-1 TNFRSF17 Immune Cell Therapy 27 P-BCMA-ALLO1 are allogeneic T lymphocytes engineered to express a single-domain variable heavy chain chimeric antigen receptor (VCAR) targeted against B-cell maturation antigen (BCMA), an undisclosed drug selection gene, and a caspase-based safety switch gene, which potentially inhibit tumor growth (Blood (2019) 134 (Supplement_1): 4445).
Rimiducid AP1903|AP-1903|AP 1903 Rimiducid (AP1903) is a small molecule that selectively binds to mutant FKBP12 and induces dimerization and downstream signaling, which can be used to activate a safety switch in transplanted cells to potentially induce apoptosis and prevent graft-versus-host disease (PMID: 9724721, PMID: 22047558, PMID: 28697888).

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.

Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.

Clinical Trial Phase Therapies Title Recruitment Status Covered Countries Other Countries
NCT04960579 Phase I P-BCMA-ALLO1 + Rimiducid Methotrexate + P-BCMA-ALLO1 + Rimiducid P-BCMA-ALLO1 Allogeneic CAR-T Cells in the Treatment of Subjects With Multiple Myeloma (MM) Recruiting USA 0


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