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Therapy Detail
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| Therapy Name | ZB716 |
| Synonyms | |
| Therapy Description |
ZB716 is a selective estrogen receptor degrader (SERD) that may inhibit growth of ESR1 (ER alpha)-positive tumor cells and decrease tumor growth (PMID: 29467940). |
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| Drug Name | Trade Name | Synonyms | Drug Classes | Drug Description |
|---|---|---|---|---|
| ZB716 | ZB 716|ZB-716|Borestrant | Hormone - Anti-estrogens 31 | ZB716 is a selective estrogen receptor degrader (SERD) that may inhibit growth of ESR1 (ER alpha)-positive tumor cells and decrease tumor growth (PMID: 29467940). |
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| Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
|---|
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| Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
|---|---|---|---|---|---|---|
| NCT04669587 | Phase Ib/II | ZB716 Palbociclib + ZB716 | ER+/HER2- Locally Advanced or Metastatic Breast Cancer (ENZENO Study) (ENZENO) | Unknown status | USA | 1 |
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