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Therapy Name | TPX-4589 |
Synonyms | |
Therapy Description |
TPX-4589 (LM-302) is an antibody-drug conjugate (ADC) comprising a claudin 18.2 (CLDN18.2) targeted antibody linked to monomethyl auristatin E (MMAE), which potentially inhibits proliferation of CLDN18.2-expressing tumor cells and tumor growth (Eur J Cancer 2022 Vol 174, Supp 1:S41-S42). |