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Therapy Name AMG 340
Synonyms
Therapy Description

AMG 340 is a T-cell engager that binds to PSMA and CD3, which potentially induces antitumor activity (J Clin Oncol 42, 2024 (suppl 16; abstr e14587).

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Drug Name Trade Name Synonyms Drug Classes Drug Description
AMG 340 AMG-340|AMG340|TNB-585|TNB 585 CD3 Antibody 99 PSMA Antibody 20 AMG 340 is a T-cell engager that binds to PSMA and CD3, which potentially induces antitumor activity (J Clin Oncol 42, 2024 (suppl 16; abstr e14587).

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

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  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.

Clinical Trial Phase Therapies Title Recruitment Status Covered Countries Other Countries
NCT04740034 Phase I AMG 340 A Study of AMG 340 in Subjects With Metastatic Castrate-Resistant Prostate Carcinoma Completed USA 0


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