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Therapy Name DCC-3009
Synonyms
Therapy Description

DCC-3009 is a KIT inhibitor with activity against exon 9 and 11 mutations, as well as mutations in exons 13, 14, 17, and 18, potentially resulting in decreased tumor growth (Cancer Res (2023) 83 (7_Supplement): 4033).

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Drug Name Trade Name Synonyms Drug Classes Drug Description
DCC-3009 DCC3009|DCC 3009 KIT Inhibitor 57 DCC-3009 is a KIT inhibitor with activity against exon 9 and 11 mutations, as well as mutations in exons 13, 14, 17, and 18, potentially resulting in decreased tumor growth (Cancer Res (2023) 83 (7_Supplement): 4033).

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

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  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References
KIT exon11 KIT exon13 gastrointestinal stromal tumor predicted - sensitive DCC-3009 Preclinical Actionable In a preclinical study, DCC-3009 induced tumor regression in a xenograft model of gastrointestinal stromal tumor harboring KIT exon 11 and exon 13 mutations (Cancer Res (2023) 83 (7_Supplement): 4033). detail...
KIT exon11 KIT exon17 gastrointestinal stromal tumor predicted - sensitive DCC-3009 Preclinical Actionable In a preclinical study, DCC-3009 induced tumor regression in a xenograft model of gastrointestinal stromal tumor harboring KIT exon 11 and exon 17 mutations (Cancer Res (2023) 83 (7_Supplement): 4033). detail...

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.

Clinical Trial Phase Therapies Title Recruitment Status Covered Countries Other Countries
NCT06630234 Phase Ib/II DCC-3009 A Master Protocol to Evaluate DCC-3009 in Gastrointestinal Stromal Tumor (GIST) Recruiting USA 0


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