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Therapy Name AZD5863
Synonyms
Therapy Description

AZD5863 is a bispecific T-cell engager targeting CLDN18.2 and CD3, which potentially induces T-cell dependent cellular cytotoxicity and tumor growth inhibition (J ImmunoTherapy Cancer 2023;11 (Suppl_1):1169).

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Drug Name Trade Name Synonyms Drug Classes Drug Description
AZD5863 AZD 5863|AZD-5863 CD3 Antibody 99 CLDN18.2 Antibody 19 AZD5863 is a bispecific T-cell engager targeting CLDN18.2 and CD3, which potentially induces T-cell dependent cellular cytotoxicity and tumor growth inhibition (J ImmunoTherapy Cancer 2023;11 (Suppl_1):1169).

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.

Clinical Trial Phase Therapies Title Recruitment Status Covered Countries Other Countries
NCT06005493 Phase Ib/II AZD5863 Study of AZD5863 in Adult Participants With Advanced or Metastatic Solid Tumors Recruiting USA | NLD | GBR | FRA 4


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