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Therapy Name | GS-9911 + Zimberelimab |
Synonyms | |
Therapy Description | |
Drug Name | Trade Name | Synonyms | Drug Classes | Drug Description |
---|---|---|---|---|
GS-9911 | GS 9911|GS9911 | Limited information is currently available on GS-9911, a putative DGKalpha inhibitor (Nov 2023). | ||
Zimberelimab | GLS-010|AB122|AB-122|GLS010 | Immune Checkpoint Inhibitor 149 PD-L1/PD-1 antibody 121 | Zimberelimab (GLS-010) is a monoclonal antibody that targets PD-1 (PDCD1) and inhibits binding of the PD-L1 (CD274) ligand, potentially resulting in enhanced anti-tumor immune response (PMID: 28679395). |
Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
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Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
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NCT06082960 | Phase I | GS-9911 + Zimberelimab GS-9911 | Study of GS-9911 With or Without Antibody Treatment for Adults With Solid Tumors | Recruiting | USA | CAN | AUS | 0 |