Therapy Detail
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| Therapy Name | BL-M07D1 |
| Synonyms | |
| Therapy Description |
BL-M07D1 is an antibody-drug conjugate (ADC) comprising the Erbb2 (Her2)-targeted monoclonal antibody trastuzumab linked to a topoisomerase I inhibitor (Ed-04), which potentially induces cell cycle arrest and apoptosis and inhibits tumor growth (Cancer Res (2023) 83 (7_Supplement): 2643). |
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| Drug Name | Trade Name | Synonyms | Drug Classes | Drug Description |
|---|---|---|---|---|
| BL-M07D1 | BLM07D1|BL M07D1 | HER2 (ERBB2) Antibody 79 HER2 (ERBB2) Antibody-Drug Conjugate 35 | BL-M07D1 is an antibody-drug conjugate (ADC) comprising the Erbb2 (Her2)-targeted monoclonal antibody trastuzumab linked to a topoisomerase I inhibitor (Ed-04), which potentially induces cell cycle arrest and apoptosis and inhibits tumor growth (Cancer Res (2023) 83 (7_Supplement): 2643). |
Filtering
- Case insensitive filtering will display rows if any text in any cell matches the filter term
- Use simple literal full or partial string matches
- Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
- Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
- Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")
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| Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
|---|
Filtering
- Case insensitive filtering will display rows if any text in any cell matches the filter term
- Use simple literal full or partial string matches
- Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
- Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
- Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")
Sorting
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- Click on any column header arrows to sort by that column
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| Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
|---|---|---|---|---|---|---|
| NCT06293898 | Phase I | BL-M07D1 | Open Label Study to Evaluate BL-M07D1 in HER2 Expressing Malignant Solid Tumors | Recruiting | USA | 0 |
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