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Therapy Name BL-M07D1
Synonyms
Therapy Description

BL-M07D1 is an antibody-drug conjugate (ADC) comprising the Erbb2 (Her2)-targeted monoclonal antibody trastuzumab linked to a topoisomerase I inhibitor (Ed-04), which potentially induces cell cycle arrest and apoptosis and inhibits tumor growth (Cancer Res (2023) 83 (7_Supplement): 2643).

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Drug Name Trade Name Synonyms Drug Classes Drug Description
BL-M07D1 BLM07D1|BL M07D1 HER2 (ERBB2) Antibody 76 HER2 (ERBB2) Antibody-Drug Conjugate 31 BL-M07D1 is an antibody-drug conjugate (ADC) comprising the Erbb2 (Her2)-targeted monoclonal antibody trastuzumab linked to a topoisomerase I inhibitor (Ed-04), which potentially induces cell cycle arrest and apoptosis and inhibits tumor growth (Cancer Res (2023) 83 (7_Supplement): 2643).

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.

Clinical Trial Phase Therapies Title Recruitment Status Covered Countries Other Countries
NCT06293898 Phase I BL-M07D1 Open Label Study to Evaluate BL-M07D1 in HER2 Expressing Malignant Solid Tumors Recruiting USA 0


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