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Therapy Name | Carboplatin + Pemetrexed Disodium + PSB205 |
Synonyms | |
Therapy Description | |
Drug Name | Trade Name | Synonyms | Drug Classes | Drug Description |
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Carboplatin | Paraplatin | CBDCA | Chemotherapy - Platinum 7 | Paraplatin (carboplatin) is a second-generation platinum compound and is activated intracellularly to form reactive platinum complexes that cross link DNA with DNA and with proteins. This induces apoptosis and inhibits cell growth (NCI Drug Dictionary). |
PSB205 | PSB-205|PSB 205|QL-1706|QL 1706|QL1706 | CTLA4 Antibody 31 PD-L1/PD-1 antibody 121 | PSB205 comprises the combination of a monoclonal antibody targeting CD274 (PD-L1) and a monoclonal antibody CTLA4, which has potential anti-tumor activity (J Clin Oncol 40, 2022 (suppl 16; abstr 2611)). | |
Pemetrexed Disodium | Alimta | LY231514|Ciambra|pemetrexed | Chemotherapy - Antimetabolite 14 | Alimta (pemetrexed disodium) is an antifolate that inhibits thymidylate synthase (NCI Drug Dictionary). |
Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
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Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
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